It's about to get a lot harder to buy knock-off Ozempic

Nicolas Ortega for BI

Jessica DeBenedetto has only been on compounded tirzepatide for a couple of weeks, but she already feels like it's a life-changer. Her doctor prescribed the cheaper, generic version of the weight-loss drug after her insurer refused to cover Zepbound, the brand-name version made by Eli Lilly. DeBenedetto, now 43, tells me she's been prediabetic since her 20s, and after going through hormone injections with IVF, she's put on a worrying amount of weight she just can't take off. As we talk, she marvels that she's had a box of chocolates on her desk all day that she still hasn't touched, which is probably the result of both the drug and a psychological shift, since she hasn't been taking the injections that long. Still, the optimism is palpable. Those chocolates would "normally be gone in an hour," she says.